ORIGINAL CONTRIBUTIONS Poliovirus Vaccination during Pregnancy, Maternal Seroconversion to Simian Virus 40, and Risk of Childhood Cancer
نویسندگان
چکیده
1 Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD. 2 Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, MD. 3 Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD. 4 Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, Rockville, MD.
منابع مشابه
Poliovirus vaccination during pregnancy, maternal seroconversion to simian virus 40, and risk of childhood cancer.
Before 1963, poliovirus vaccine produced in the United States was contaminated with simian virus 40 (SV40), which causes cancer in animals. To examine whether early-life SV40 infection can cause human cancer, the authors studied 54,796 children enrolled in the US-based Collaborative Perinatal Project (CPP) in 1959-1966, 52 of whom developed cancer by their eighth birthday. Those children whose ...
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متن کاملRe: Cancer incidence in Denmark following exposure to poliovirus vaccine contaminated with simian virus 40.
BACKGROUND Early poliovirus vaccines were accidentally contaminated with simian virus 40 (SV40). In Denmark, poliovirus vaccine was administered to most children from 1955 through 1961. SV40 DNA sequences have been detected in several human malignancies, including mesothelioma, ependymoma, choroid plexus tumors, and non-Hodgkin's lymphoma. To clarify whether SV40 infection increases risk of the...
متن کاملCORRESPONDENCE Re: Cancer Incidence in Denmark Following Exposure to Poliovirus Vaccine Contaminated With Simian Virus
We read with interest the recent article by Engels et al. (1) in which the authors performed a retrospective birthcohort analysis in Denmark following exposure to poliovirus vaccine contaminated with simian virus 40 (SV40) to clarify whether SV40 infection increases risk of mesothelioma, choroid plexus tumors, and non-Hodgkin’s lymphoma, or of cancers arising in children. The authors concluded ...
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BACKGROUND The final endgame strategy of global polio eradication initiative includes switching from trivalent oral poliovirus vaccines (tOPV) to bivalent oral polio vaccine (bOPV), and introduction of inactivated poliovirus vaccine (IPV). This study compares IPV with tOPV week 39 boost in Indian infants. METHODS Starting 28 March 2012, we enrolled 372 Indian infant-mother pairs from Kolkata,...
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